Modifications

Marco Ruggiero (voir la source)

Version du 21 février 2017 à 16:45

1 061 octets ajoutés , 21 février 2017 à 16:45

Ligne 62 : Ligne 62 :

== Liens externes ==

* https://www.youtube.com/watch?v=Bu0AuPo50_k Intervento del Prof. Ruggiero al convegno mondiale sul Gcmaf a Francoforte (1° parte), (Intervention de Marco Rugiero lors du 1er congrès GcMAF à Frankfurt en avril 2013)

−

* http://scholarlyoa.com/2014/07/24/would-you-take-a-cancer-cure-proven-effective-in-a-predatory-journal/ (Prendriez-vous un traitement prouvé efficace dans un journal prédateur ?) ~~publié le 5 août 2014~~. Il s'agit d'un article publié par Jeffrey Beall<ref>https://en.wikipedia.org/wiki/Jeffrey_Beall</ref>, créateur de la "list of predatory publishers" (liste des journaux prédateurs) ~~appelée fréquemment la~~ "liste de Beall". A la mi-janvier 2017, Beall a supprimé cette liste sans expliquer le pourquoi de cette suppression. La communauté scientifique déplore cette suppression qui était une source utile de renseignement. L'article cité n'est donc plus accessible depuis cette date, sauf peut-être sous forme d'archive, et ici. I am writing this blog post in hopes of starting a conversation in the scientific community about the medicine called [[GcMAF]] and one of the companies that is currently distributing it, a company called GcMAF.eu [[GcMAF]] means “Gc protein-derived macrophage activating factor,” according to the short article about it on Wikipedia. The drug is currently being marketed as a cure for many ailments, including cancer, autism, MS and Parkinson’s disease. I am concerned about this drug and its marketing for these reasons: 1. Apparently, some of the same people who are researching the drug also are involved in marketing and selling it. 2. Some (not all) of their research has been published in questionable journals, including one published by a publisher that is on my list. 3. The drug is not approved by any competent authority (FDA, EMA) to treat any disease. The following three articles report favorably on [[GcMAF]] and appear in the American Journal of Immunology a journal published by Science Publications, a publisher on my list. The three articles are: 1.Thyer, L., Ward, E., Smith, R., Branca, J. J. V., Morucci, G., Gulisano, M., [[David Noakes|Noakes, D.]] & Pacini, S. (2013). Therapeutic effects of highly purified de-glycosylated [[GcMAF]] in the immunotherapy of patients with chronic diseases. American Journal of Immunology, 9(3), 78-84.<ref>http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738989/ Article "Therapeutic effects of highly purified de-glycosylated [[GcMAF]] in the immunotherapy of patients with chronic diseases"</ref> 2.Smith, R., Thyer, L., Ward, E., Meacci, E., Branca, J. J. V., Morucci, G., Gulisano, M. R., Ruggiero, M., Pacini, A, Paternostro, F., Di Cesare Mannelli, L., [[David Noakes|Noakes, D. J.]], & Pacini, S. (2013). Effects of Gc-macrophage activating factor in human neurons; implications for treatment of chronic fatigue syndrome. American Journal of Immunology, 9(4), 120-129.<ref>http://thescipub.com/PDF/ajisp.2013.120.129.pdf Article "Effects of Gc-macrophage activating factor in human neurons; implications for treatment of chronic fatigue syndrome"</ref> 3.Ward, E., Smith, R., Branca, J. J. V., [[David Noakes|Noakes, D.]], Morucci, G., & Thyer, L. (2014). Clinical Experience of Cancer Immunotherapy Integrated with Oleic Acid Complexed with De-Glycosylated Vitamin D Binding Protein. American Journal of Immunology, 10(1), 23-32.<ref>http://www.legamberifoods.com/polopoly_fs/1.155809.1411607941!/httpFile/file.pdf Article "Clinical Experience of Cancer Immunotherapy Integrated with Oleic Acid Complexed with De-Glycosylated Vitamin D Binding Protein"</ref> The first and the third articles report the authors’ experience with patients treated at the Immuno Biotech Treatment Center. From their website one sees that the cost is €6,000 a week for the center, and their hotel cost estimate is €1,800. This price is significantly higher than the €600 they charge for the [[GcMAF]] ampule alone. These patients have been an important source of revenue for this company. As far as I can tell, none of the authors discloses affiliation to this center, so it is not clear who treated the patients. Moreover, there is no other information on this treatment center than the information on these articles and the website of this company. Thus it is rather strange that patients have to have a separate budget for their accommodation, which means there are being treated as outpatients. What is the point on making them travel to receive a treatment that could be given on an outpatient basis by one of the 350 doctors around the world claimed to be using [[GcMAF]]? The publisher of the journal, Science Publications, lists two addresses on its “Contact Us” page, one in Adelaide, SA, Australia and one in New York, NY, USA. I think both addresses are really those of mail-forwarding services and the publisher is hiding its true location, which remains unknown. Why are these scientists publishing their work in a highly questionable journal operated by a non-transparent publisher? If the work is so groundbreaking (a cure for cancer, et al.), why not publish it in a legitimate journal where its impact would be greater, its conclusions more convincing? Do any of the authors have any declarable conflicts of interest? If so, what are they? Where can I find them? On the [[GcMAF]].eu website, the site of the company that sells the potion, under the “Who we are” link, it says this: We are a group of scientists led by Professor Marco Ruggiero MD, a molecular biologist and fully qualified medical doctor. The team includes a PhD and two BSc biomedical scientists. External doctors, oncologists and scientists kindly provide help and advice. We are committed to bringing [[GcMAF]] and its associated treatments to as many people as we can. Ruggiero is listed as one of the authors of one of the articles above, so I assume the other authors are part of his team and are associated with the company [[GcMAF]].eu. One of the first scientists to research [[GcMAF]] was Nobuto Yamamoto, but his 2007 article on the compound was retracted. Regarding pricing, the company’s website states Our GcMAF is €600, plus €60 packing and shipping, for one 2.2ml vial. A vial is one third full and contains up to eight doses – one 100ng, 0.25ml dose a week. I found the overall tone of the [[GcMAF]] website to be mean and self-righteous. It makes a lot of claims such as “Root canals are a major cause of the immune system being suppressed and they are a major cause of cancer.” Is the published science behind [[GcMAF]] authentic, honest, and real? I ask that the bio-medical sciences community investigate this compound, the science behind it, and its marketing. Coda: A good analysis of GcMAF is available from the Anticancer Fund here.

+

* http://scholarlyoa.com/2014/07/24/would-you-take-a-cancer-cure-proven-effective-in-a-predatory-journal/ (Prendriez-vous un traitement pour le cancer prouvé efficace dans un journal prédateur ?). Il s'agit d'un article publié le 24 juillet 2014 par Jeffrey Beall<ref>https://en.wikipedia.org/wiki/Jeffrey_Beall</ref>, créateur de la "list of predatory publishers" (liste des journaux prédateurs) connue sous le nom de "liste de Beall". A la mi-janvier 2017, Beall a supprimé cette liste sans expliquer le pourquoi de cette suppression. La communauté scientifique déplore cette suppression qui était une source utile de renseignement. L'article cité n'est donc plus accessible depuis cette date, sauf peut-être sous forme d'archive, et ici. I am writing this blog post in hopes of starting a conversation in the scientific community about the medicine called [[GcMAF]] and one of the companies that is currently distributing it, a company called GcMAF.eu [[GcMAF]] means “Gc protein-derived macrophage activating factor,” according to the short article about it on Wikipedia. The drug is currently being marketed as a cure for many ailments, including cancer, autism, MS and Parkinson’s disease. I am concerned about this drug and its marketing for these reasons: 1. Apparently, some of the same people who are researching the drug also are involved in marketing and selling it. 2. Some (not all) of their research has been published in questionable journals, including one published by a publisher that is on my list. 3. The drug is not approved by any competent authority (FDA, EMA) to treat any disease. The following three articles report favorably on [[GcMAF]] and appear in the American Journal of Immunology a journal published by Science Publications, a publisher on my list. The three articles are: 1.Thyer, L., Ward, E., Smith, R., Branca, J. J. V., Morucci, G., Gulisano, M., [[David Noakes|Noakes, D.]] & Pacini, S. (2013). Therapeutic effects of highly purified de-glycosylated [[GcMAF]] in the immunotherapy of patients with chronic diseases. American Journal of Immunology, 9(3), 78-84.<ref>http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738989/ Article "Therapeutic effects of highly purified de-glycosylated [[GcMAF]] in the immunotherapy of patients with chronic diseases"</ref> 2.Smith, R., Thyer, L., Ward, E., Meacci, E., Branca, J. J. V., Morucci, G., Gulisano, M. R., Ruggiero, M., Pacini, A, Paternostro, F., Di Cesare Mannelli, L., [[David Noakes|Noakes, D. J.]], & Pacini, S. (2013). Effects of Gc-macrophage activating factor in human neurons; implications for treatment of chronic fatigue syndrome. American Journal of Immunology, 9(4), 120-129.<ref>http://thescipub.com/PDF/ajisp.2013.120.129.pdf Article "Effects of Gc-macrophage activating factor in human neurons; implications for treatment of chronic fatigue syndrome"</ref> 3.Ward, E., Smith, R., Branca, J. J. V., [[David Noakes|Noakes, D.]], Morucci, G., & Thyer, L. (2014). Clinical Experience of Cancer Immunotherapy Integrated with Oleic Acid Complexed with De-Glycosylated Vitamin D Binding Protein. American Journal of Immunology, 10(1), 23-32.<ref>http://www.legamberifoods.com/polopoly_fs/1.155809.1411607941!/httpFile/file.pdf Article "Clinical Experience of Cancer Immunotherapy Integrated with Oleic Acid Complexed with De-Glycosylated Vitamin D Binding Protein"</ref> The first and the third articles report the authors’ experience with patients treated at the Immuno Biotech Treatment Center. From their website one sees that the cost is €6,000 a week for the center, and their hotel cost estimate is €1,800. This price is significantly higher than the €600 they charge for the [[GcMAF]] ampule alone. These patients have been an important source of revenue for this company. As far as I can tell, none of the authors discloses affiliation to this center, so it is not clear who treated the patients. Moreover, there is no other information on this treatment center than the information on these articles and the website of this company. Thus it is rather strange that patients have to have a separate budget for their accommodation, which means there are being treated as outpatients. What is the point on making them travel to receive a treatment that could be given on an outpatient basis by one of the 350 doctors around the world claimed to be using [[GcMAF]]? The publisher of the journal, Science Publications, lists two addresses on its “Contact Us” page, one in Adelaide, SA, Australia and one in New York, NY, USA. I think both addresses are really those of mail-forwarding services and the publisher is hiding its true location, which remains unknown. Why are these scientists publishing their work in a highly questionable journal operated by a non-transparent publisher? If the work is so groundbreaking (a cure for cancer, et al.), why not publish it in a legitimate journal where its impact would be greater, its conclusions more convincing? Do any of the authors have any declarable conflicts of interest? If so, what are they? Where can I find them? On the [[GcMAF]].eu website, the site of the company that sells the potion, under the “Who we are” link, it says this: We are a group of scientists led by Professor Marco Ruggiero MD, a molecular biologist and fully qualified medical doctor. The team includes a PhD and two BSc biomedical scientists. External doctors, oncologists and scientists kindly provide help and advice. We are committed to bringing [[GcMAF]] and its associated treatments to as many people as we can. Ruggiero is listed as one of the authors of one of the articles above, so I assume the other authors are part of his team and are associated with the company [[GcMAF]].eu. One of the first scientists to research [[GcMAF]] was Nobuto Yamamoto, but his 2007 article on the compound was retracted. Regarding pricing, the company’s website states Our GcMAF is €600, plus €60 packing and shipping, for one 2.2ml vial. A vial is one third full and contains up to eight doses – one 100ng, 0.25ml dose a week. I found the overall tone of the [[GcMAF]] website to be mean and self-righteous. It makes a lot of claims such as “Root canals are a major cause of the immune system being suppressed and they are a major cause of cancer.” Is the published science behind [[GcMAF]] authentic, honest, and real? I ask that the bio-medical sciences community investigate this compound, the science behind it, and its marketing. Coda: A good analysis of GcMAF is available from the Anticancer Fund here.

* http://www.anticancerfund.org/fr/news/gcmaf-for-the-treatment-of-breast-cancer-retraction-of-an-article-by-yamamoto-et-al Rétraction d'un article de Yamamto et al. concernant le [[GcMAF]] en tant que traitement du cancer du sein

* http://journal.frontiersin.org/article/10.3389/fnhum.2013.00934/abstract Papier "A new methodology of viewing extra-axial fluid and cortical abnormalities in children with autism via transcranial ultrasonography", auteurs : [[Jeff Bradstreet|James Jeffrey Bradstreet]], Stefania Pacini and Marco Ruggiero, publié le 15 janvier 2014 dans la revue Frontiers in Human Neuroscience.

−

* http://www.bravo-probiotics.com/wholesale.html Le Bravo Probiotic de Ruggiero en 2017. Si on clique sur "Online Clinic", on constate que ce site est administré par le "Dr Jeremy & Clive de Carle". L'onglet "shop" conduit à un site marchand <ref>http://www.naturallybettershop.com/bravo-probiotics---the-best-in-the-world.html</ref> où on trouve, entre autres, le ~~BravoProbiotic~~ et le "Dr Jeremy & Clive de Carle"

+

* http://www.bravo-probiotics.com/wholesale.html Le Bravo Probiotic de Ruggiero en 2017. Si on clique sur "Online Clinic", on constate que ce site est administré par le "Dr Jeremy & Clive de Carle". L'onglet "shop" conduit à un site marchand <ref>http://www.naturallybettershop.com/bravo-probiotics---the-best-in-the-world.html</ref> où on trouve, entre autres, le Bravo Probiotic et le "Dr Jeremy & Clive de Carle"

* https://www.youtube.com/watch?v=lSdYdyF5agA Vidéo intitulée "RERUM and BRAVO. The Health Revolution. Dr Marco Ruggiero MD. Phd. speaks with Clive de Carle.

−

* https://www.thesun.co.uk/archives/news/1122183/health-guru-clive-de-carle-accused-of-selling-potentially-deadly-autism-cure-pill-to-desperate-parents-trying-to-help-their-kids/

+

* https://www.thesun.co.uk/archives/news/1122183/health-guru-clive-de-carle-accused-of-selling-potentially-deadly-autism-cure-pill-to-desperate-parents-trying-to-help-their-kids/ ‘Health guru’ Clive de Carle accused of selling potentially deadly autism ‘cure’ pill to desperate parents trying to help their kids (Le 'Gourou de la santé' Clive de Carle accusé de vendre des pilules 'guérissant' l'autisme potentiellement mortelles à des parents désespérés essayant d'aider leurs enfants EXCLUSIVE: Quack caught out promoting lethal drug (Le charlatan s'est fait pincer faisant la promotion d'un médicament létal). Par Michael Hamilton, 9th April 2016. Clive de Carle, 60 ans, offrait de vendre du Rerum, qui est une forme plus forte du produit non autorisé [[GcMAF]] et une solution de blanchiment [[MMS]]. Il fait la promotion de ses thérapies alternatives sur son site Web Health Revolution. Mais la Medicines and Healthcare Products Regulatory Agency (Agence de réglementation des médicaments et des produits de santé) avertit que le [[GcMAF]] présente un «risque grave» pour la santé. Elle a aussi publié des avertissements à propos du [[MMS]] qui a été lié à au moins un décès.

Pascal

12 795

modifications