Différences entre les versions de « Robert Nataf »

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== Les publications de Mr Nataf ==
 
== Les publications de Mr Nataf ==
 
=== L'étude de 2006 ===
 
=== L'étude de 2006 ===
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=== L'étude de 2008 ===
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=== L'étude de 2009 ===
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Nataf est co-auteur avec Mark Geier d'une étude publiée en 2008 dans Journal of the Neurological Sciences (JNS-10672; No of Pages 8). L'adresse du journal : Mark R. Geier, 14 Redgate Ct., Silver Spring, MD 20905. Cette étude a été signalée, commentée et saluée dans les pages en français d'Autism Treatment Institute<ref>http://www.autism.com/trans_french_ARRIV22No32008mercury</ref>.
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Nataf est co-auteur avec Mark Geier d'une étude publiée le 9 Janvier 2009 dans Journal of the Neurological Sciences (JNS-10672; No of Pages 8). L'adresse du journal : Mark R. Geier, 14 Redgate Ct., Silver Spring, MD 20905. Cette étude a été signalée, commentée et saluée dans les pages en français d'Autism Treatment Institute<ref>http://www.autism.com/trans_french_ARRIV22No32008mercury</ref>.
  
 
Ici, le détail de l'étude<ref>http://webcache.googleusercontent.com/search?q=cache:ySEHsBmqMngJ:www.drd411.com/storage/documents/Biomarkers_of_Environmental_Toxicity__Susceptibilty_in_Autism_In_Press1.pdf+&cd=7&hl=fr&ct=clnk&gl=fr Le document a été supprimé, il n'en reste plus que le cache.</ref>: <br>Journal of the Neurological Sciences<br>Biomarkers of environmental toxicity and susceptibility in autism<br>David A. Geier a,b, Janet K. Kern c,d, Carolyn R. Garver c, James B. Adams e, Tapan Audhya f,Robert Nataf g, Mark R. Geier h<br> - a Institute of Chronic Illnesses, Inc., Silver Spring, Maryland, USA<br> - b CoMeD, Inc., Silver Spring, Maryland, USA<br> - c Autism Treatment Center, Dallas, Texas, USA<br> - d University of Texas Southwestern Medical Center, Dallas, Texas, USA<br> - e Arizona State University, Tempe, Arizona, USA<br> - f Vitamin Diagnostics, Cliffwood Beach, New Jersey, USA<br> - g Laboratoire Philippe Auguste, Paris, France<br> - h The Genetic Centers of America, Silver Spring, Maryland, USA<br><br>Article history:Received 21 May 2008. Received in revised form 11 August 2008. Accepted 15 August 2008. Available online xxxx<br><br> Abstract: Autism spectrum disorders (ASDs) may result from a combination of genetic/biochemical susceptibilities inthe form of a reduced ability to excrete mercury and/or increased environmental exposure at keydevelopmental times. Urinary porphyrins and transsulfuration metabolites in participants diagnosed with anASD were examined. A prospective, blinded study was undertaken to evaluate a cohort of 28 participantswith an ASD diagnosis for Childhood Autism Rating Scale (CARS) scores, urinary porphyrins, andtranssulfuration metabolites. Testing was conducted using Vitamin Diagnostics, Inc. (CLIA-approved) and Laboratoire Philippe Auguste (ISO-approved). Participants with severe ASDs had significantly increasedmercury intoxication-associated urinary porphyrins (pentacarboxyporphyrin, precoproporphyrin, andcoproporphyrin) in comparison to participants with mild ASDs, whereas other urinary porphyrins weresimilar in both groups. Significantly decreased plasma levels of reduced glutathione (GSH), cysteine, andsulfate were observed among study participants relative to controls. In contrast, study participants hadsignificantly increased plasma oxidized glutathione (GSSG) relative to controls. Mercury intoxication-associated urinary porphyrins were significantly correlated with increasing CARS scores and GSSG levels,whereas other urinary porphyrins did not show these relationships. The urinary porphyrin and CARS scorecorrelations observed among study participants suggest that mercury intoxication is significantly associatedwith autistic symptoms. The transsulfuration abnormalities observed among study participants indicate thatmercury intoxication was associated with increased oxidative stress and decreased detoxification capacity.<br><br>☆ Study Funding: This research was funded by a grant from the Autism Research Institute, the non-profit CoMeD, Inc., and by the non-profit Institute of Chronic Illnesses,Inc. through a grant from the Brenen Hornstein Autism Research & Education (BHARE)Foundation. Potential Conflicts of Interest: David Geier, Janet Kern, James Adams, and Mark Geier have been involved in vaccine/biologic litigation. Robert Nataf and TapanAudhya are affiliated with the labs used to test the study participants.
 
Ici, le détail de l'étude<ref>http://webcache.googleusercontent.com/search?q=cache:ySEHsBmqMngJ:www.drd411.com/storage/documents/Biomarkers_of_Environmental_Toxicity__Susceptibilty_in_Autism_In_Press1.pdf+&cd=7&hl=fr&ct=clnk&gl=fr Le document a été supprimé, il n'en reste plus que le cache.</ref>: <br>Journal of the Neurological Sciences<br>Biomarkers of environmental toxicity and susceptibility in autism<br>David A. Geier a,b, Janet K. Kern c,d, Carolyn R. Garver c, James B. Adams e, Tapan Audhya f,Robert Nataf g, Mark R. Geier h<br> - a Institute of Chronic Illnesses, Inc., Silver Spring, Maryland, USA<br> - b CoMeD, Inc., Silver Spring, Maryland, USA<br> - c Autism Treatment Center, Dallas, Texas, USA<br> - d University of Texas Southwestern Medical Center, Dallas, Texas, USA<br> - e Arizona State University, Tempe, Arizona, USA<br> - f Vitamin Diagnostics, Cliffwood Beach, New Jersey, USA<br> - g Laboratoire Philippe Auguste, Paris, France<br> - h The Genetic Centers of America, Silver Spring, Maryland, USA<br><br>Article history:Received 21 May 2008. Received in revised form 11 August 2008. Accepted 15 August 2008. Available online xxxx<br><br> Abstract: Autism spectrum disorders (ASDs) may result from a combination of genetic/biochemical susceptibilities inthe form of a reduced ability to excrete mercury and/or increased environmental exposure at keydevelopmental times. Urinary porphyrins and transsulfuration metabolites in participants diagnosed with anASD were examined. A prospective, blinded study was undertaken to evaluate a cohort of 28 participantswith an ASD diagnosis for Childhood Autism Rating Scale (CARS) scores, urinary porphyrins, andtranssulfuration metabolites. Testing was conducted using Vitamin Diagnostics, Inc. (CLIA-approved) and Laboratoire Philippe Auguste (ISO-approved). Participants with severe ASDs had significantly increasedmercury intoxication-associated urinary porphyrins (pentacarboxyporphyrin, precoproporphyrin, andcoproporphyrin) in comparison to participants with mild ASDs, whereas other urinary porphyrins weresimilar in both groups. Significantly decreased plasma levels of reduced glutathione (GSH), cysteine, andsulfate were observed among study participants relative to controls. In contrast, study participants hadsignificantly increased plasma oxidized glutathione (GSSG) relative to controls. Mercury intoxication-associated urinary porphyrins were significantly correlated with increasing CARS scores and GSSG levels,whereas other urinary porphyrins did not show these relationships. The urinary porphyrin and CARS scorecorrelations observed among study participants suggest that mercury intoxication is significantly associatedwith autistic symptoms. The transsulfuration abnormalities observed among study participants indicate thatmercury intoxication was associated with increased oxidative stress and decreased detoxification capacity.<br><br>☆ Study Funding: This research was funded by a grant from the Autism Research Institute, the non-profit CoMeD, Inc., and by the non-profit Institute of Chronic Illnesses,Inc. through a grant from the Brenen Hornstein Autism Research & Education (BHARE)Foundation. Potential Conflicts of Interest: David Geier, Janet Kern, James Adams, and Mark Geier have been involved in vaccine/biologic litigation. Robert Nataf and TapanAudhya are affiliated with the labs used to test the study participants.

Version du 6 mai 2014 à 16:47

Robert Nataf vers 2009. Source les vidéos du film Silence, on Vaccine[1]

Robert Nataf est un médecin biologiste directeur et fondateur du Laboratoire Philippe Auguste à Paris, connu pour son étude controversée (publiée le 15 juillet 2006 dans la revue Toxicology and Applied Pharmacology) proposant une association entre l'autisme infantile et les toxines environnementales, en particulier le mercure.[2][3][4]. Nataf avait à l'origine dit aux parents qu'il avait une publication dans la revue The Lancet Neurology, mais les éditeurs du Lancet ont nié l'existence d'un tel document, et Nataf a refusé de clarifier la situation lorsqu'on lui a demandé de commenter[5]. Nataf a avancé l'idée que la toxicité du mercure peut être une cause de l'autisme à diverses conférences, comme au États-Unis sur l'autisme et à la conférence annuelle d'Asperger Association[6]. Il a aussi mené d'autres recherches avec Mark Geier[7] et sur le lien potentiel entre la toxicité du mercure et l'autisme, tel qu'il se manifeste à divers dans certaines porphyrines urinaires.[8]. Cependant, Kevin Leitch du blog LeftBrainRightBrain[9] a remis en cause la recherche de Nataf, arguant que les niveaux de précoproporphyrine n'étaient pas, comme Nataf l'avait avancé dans son article de 2006, nécessairement indicatif de la toxicité du mercure[10]. D'autres critiques ont noté que Laboratoire Philippe Auguste vend des tests de porphyrine et que Nataf peut donc avoir un conflit d'intérêts[5] [11].

Formation

Robert Nataf a obtenu son doctorat en médecine de l'Université de Paris VII (Paris Diderot) et a reçu les certifications en bactériologie clinique et virologie, en immunologie générale, en hématologie et en biochimie clinique[12].

Les publications de Mr Nataf

L'étude de 2006

L'étude de 2009

Nataf est co-auteur avec Mark Geier d'une étude publiée le 9 Janvier 2009 dans Journal of the Neurological Sciences (JNS-10672; No of Pages 8). L'adresse du journal : Mark R. Geier, 14 Redgate Ct., Silver Spring, MD 20905. Cette étude a été signalée, commentée et saluée dans les pages en français d'Autism Treatment Institute[13].

Ici, le détail de l'étude[14]:
Journal of the Neurological Sciences
Biomarkers of environmental toxicity and susceptibility in autism
David A. Geier a,b, Janet K. Kern c,d, Carolyn R. Garver c, James B. Adams e, Tapan Audhya f,Robert Nataf g, Mark R. Geier h
- a Institute of Chronic Illnesses, Inc., Silver Spring, Maryland, USA
- b CoMeD, Inc., Silver Spring, Maryland, USA
- c Autism Treatment Center, Dallas, Texas, USA
- d University of Texas Southwestern Medical Center, Dallas, Texas, USA
- e Arizona State University, Tempe, Arizona, USA
- f Vitamin Diagnostics, Cliffwood Beach, New Jersey, USA
- g Laboratoire Philippe Auguste, Paris, France
- h The Genetic Centers of America, Silver Spring, Maryland, USA

Article history:Received 21 May 2008. Received in revised form 11 August 2008. Accepted 15 August 2008. Available online xxxx

Abstract: Autism spectrum disorders (ASDs) may result from a combination of genetic/biochemical susceptibilities inthe form of a reduced ability to excrete mercury and/or increased environmental exposure at keydevelopmental times. Urinary porphyrins and transsulfuration metabolites in participants diagnosed with anASD were examined. A prospective, blinded study was undertaken to evaluate a cohort of 28 participantswith an ASD diagnosis for Childhood Autism Rating Scale (CARS) scores, urinary porphyrins, andtranssulfuration metabolites. Testing was conducted using Vitamin Diagnostics, Inc. (CLIA-approved) and Laboratoire Philippe Auguste (ISO-approved). Participants with severe ASDs had significantly increasedmercury intoxication-associated urinary porphyrins (pentacarboxyporphyrin, precoproporphyrin, andcoproporphyrin) in comparison to participants with mild ASDs, whereas other urinary porphyrins weresimilar in both groups. Significantly decreased plasma levels of reduced glutathione (GSH), cysteine, andsulfate were observed among study participants relative to controls. In contrast, study participants hadsignificantly increased plasma oxidized glutathione (GSSG) relative to controls. Mercury intoxication-associated urinary porphyrins were significantly correlated with increasing CARS scores and GSSG levels,whereas other urinary porphyrins did not show these relationships. The urinary porphyrin and CARS scorecorrelations observed among study participants suggest that mercury intoxication is significantly associatedwith autistic symptoms. The transsulfuration abnormalities observed among study participants indicate thatmercury intoxication was associated with increased oxidative stress and decreased detoxification capacity.

☆ Study Funding: This research was funded by a grant from the Autism Research Institute, the non-profit CoMeD, Inc., and by the non-profit Institute of Chronic Illnesses,Inc. through a grant from the Brenen Hornstein Autism Research & Education (BHARE)Foundation. Potential Conflicts of Interest: David Geier, Janet Kern, James Adams, and Mark Geier have been involved in vaccine/biologic litigation. Robert Nataf and TapanAudhya are affiliated with the labs used to test the study participants.

Depuis, Mark Geier s'est vu retirer son autorisation d'exercer dans presque la totalité des états des USA[15].

Participation à divers évènements

[16] 

Cet article est partiellement ou en totalité issu d'un article du Wikipédia anglais

Références

  1. ↑ https://www.youtube.com/watch?v=CMYe1ZSM9P4 Vidéo 2 faisant partie des 9 vidéos qui rediffusent le film "Silence, on vaccine". On voit Robert Nataf au milieu de la vidéo faisant suite, entre autre, à l'intervention de Mark Geier. Andrew Wakefield intervient dans les vidéos 7, 8 et 9 de cette série. Le film est une coproduction franco-canadienne où figurent les partisans de Wakdefield et les opposants à la vaccination français, canadiens et américains.
  2. ↑ http://www.bodiesinrebellion.com/porphyrinuria.pdf Titre du document: Porphyrinuria in childhood autistic disorder : Implications for environmental toxicity.
    Auteurs: NATAF Robert (1) ; SKORUPKA Corinne (2) ; AMET Lorene (2) ; LAM Alain (1) ; SPRINGBETT Anthea (3) ; LATHE Richard (4) .
    (1) Laboratoire Philippe Auguste, Paris, FRANCE
    (2) Association ARIANE, Clichy, FRANCE
    (3) Department of Statistics, Roslin Institute, Roslin, ROYAUME-UNI
    (4) Pieta Research, PO Box 27069, Edinburgh EH10 5YW, ROYAUME-UNI
    Revue: Toxicology and applied pharmacology
    Publié en 2006
  3. ↑ http://www.newscientist.com/article/mg19025535.400 Article "Heavy metals may be implicated in autism", publié le 30 mai 2006 dans le magazine le New Scientist
  4. ↑ http://www.huffingtonpost.com/lisa-conte/advocacy-for-autism-answe_b_113321.html Article "Advocacy for Autism Answers-- Understanding Ubiquitous Mercury", par Lisa Conte, publié le 18 juillet 2008 dans huffingtonpost (anglais)
  5. ↑ 5,0 et 5,1 http://www.newscientist.com/data/pdf/press/2609/260906.pdf Article en anglais: US Vaccines on Trial Over Link to Autism. Par Giles, Jim. Publié le 23 juin 2007
  6. ↑ http://www.usautism.org/USAAA_Newsletter/usaaa_newsletter_2006/100406_newsletter.htm October 4, 2006 Newsletter]
  7. ↑ https://en.wikipedia.org/wiki/Mark_Geier Article du wikipedia-anglais sur Mark Geier, médecin et généticien américain controversé, partie prenante dans la polémique sur l'autisme, opposant à la vaccination, à qui a été retiré l'autorisation d'exercer en 2011
  8. ↑ Geier, D. A.; Kern, J. K.; Garver, C. R.; Adams, J. B.; Audhya, T.; Nataf, R.; Geier, M. R. (2009). J Neurol Sci. 2009 May 15;280(1-2):101-8. doi: 10.1016/j.jns.2008.08.021. Epub 2008 Sep 25. "Biomarkers of environmental toxicity and susceptibility in autism". Journal of the Neurological Sciences
  9. ↑ http://leftbrainrightbrain.co.uk/ Le Blog "Autism Science, News and Opinions" de Kevin Leitch
  10. ↑ Article "Defeating Autism: A Damaging Delusion", par Michael Fritzpatrick dans Routledge en 2009. Voir page 67
  11. ↑ http://www.newscientist.com/data/pdf/press/2609/260906.pdf Article en anglais intitulé "US vaccines on trial over link to autism (Vaccins américains au procès sur le lien avec l'autisme)", paru le 23 juin 2007 dans la revue New Scientist, évoquant les conflits d'intérêts que Nataf a omis de signaler lors de la parution de son article de recherche. Le même reproche est fait à l'américain Mark Geier avec lequel Nataf publira ultérieurement un autre article de recherche en 2008.
  12. ↑ http://www.autismmedia.org/media4.html
  13. ↑ http://www.autism.com/trans_french_ARRIV22No32008mercury
  14. ↑ http://webcache.googleusercontent.com/search?q=cache:ySEHsBmqMngJ:www.drd411.com/storage/documents/Biomarkers_of_Environmental_Toxicity__Susceptibilty_in_Autism_In_Press1.pdf+&cd=7&hl=fr&ct=clnk&gl=fr Le document a été supprimé, il n'en reste plus que le cache.
  15. ↑ http://www.stltoday.com/news/local/metro/controversial-autism-doctor-loses-license-elsewhere-but-can-still-practice/article_3dd4aac0-675f-5998-84f3-beb29468d36b.html?utm_medium=twitter&utm_source=twitterfeed Controversial autism doctor loses license elsewhere, but can still practice in Missouri, Illinois Publié le 04/10/2013 (anglais)
  16. ↑ http://chronimed.over-blog.com/article-l-office-national-du-film-du-canada-presente-silence-on-vaccine-71392402.html 
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