| In 2004, the veterinary institute of the Ludwig-Maximilians-University in Munich examined "night milk" in another study<ref>Wöhr, A.C., Birkle J., Unshelm J., Erhard M.H. ''MELATONIN IN `NIGHT MILK´ AND THE USE AS FUNCTIONAL FOOD'', 23rd World Buiatrics Congress, Quebec City, Canada, Juli 2004</ref>. The munich researcher detected that milk drawn from cows at night contained 18.7 pg/ml melatonin. During daytime milking only 1.9 pg/ml melatonin were detected. High variation within the population was noticed. In a feeding experiment with night milk and ordinary milk given to calves, no effect on their circadian rhythm nor on the plasma concentration became evident. Therefore, the authors concluded, night milk has no effect as a pacemaker (melatonin acts as s pacemaker and has a so called Zeitgeber function). The melatonin signal forms part of the system that regulates the sleep-wake cycle. It is the central nervous system (more specifically, the SCN, supra chiasmatic nuclei) that controls the daily cycle in most components of the paracrine and endocrine systems rather than the melatonin signal (as was once postulated). | | In 2004, the veterinary institute of the Ludwig-Maximilians-University in Munich examined "night milk" in another study<ref>Wöhr, A.C., Birkle J., Unshelm J., Erhard M.H. ''MELATONIN IN `NIGHT MILK´ AND THE USE AS FUNCTIONAL FOOD'', 23rd World Buiatrics Congress, Quebec City, Canada, Juli 2004</ref>. The munich researcher detected that milk drawn from cows at night contained 18.7 pg/ml melatonin. During daytime milking only 1.9 pg/ml melatonin were detected. High variation within the population was noticed. In a feeding experiment with night milk and ordinary milk given to calves, no effect on their circadian rhythm nor on the plasma concentration became evident. Therefore, the authors concluded, night milk has no effect as a pacemaker (melatonin acts as s pacemaker and has a so called Zeitgeber function). The melatonin signal forms part of the system that regulates the sleep-wake cycle. It is the central nervous system (more specifically, the SCN, supra chiasmatic nuclei) that controls the daily cycle in most components of the paracrine and endocrine systems rather than the melatonin signal (as was once postulated). |
− | No food has been found so far to elevate plasma melatonin levels in humans. | + | No food has been found so far to elevate plasma melatonin levels in humans.<ref>Coates, Paul M. (2005). "Encyclopedia of Dietary Supplements". Marc R. Blackman, Gordon M. Cragg, Mark Levine, Joel Moss, Jeffrey D. White. CRC Press. pp. 457–466. ISBN 0824755049</ref> |