− | Im Grenzgebiet zwischen Thailand und Kambodscha beobachtet die Weltgesundheitsorganisation (WHO) zunehmend Resistenzen gegen das Malariamittel Artemisinin, das von der WHO kampagnenmässig gegen die Malaria beworben wurde<ref>Duffy PE, Sibley CH. Are we losing artemisinin combination therapy already? Lancet 2005;366:1908-1909</ref><ref>Jambou R, Legrand E, Niang M, et al. Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6. Lancet 2005;366:1960-1963</ref><ref>Noedl H. Artemisinin resistance: how can we find it? Trends Parasitol 2005;21:404-405</ref><ref>Quashie, N. B. (2009). Detection of Artemisinin-resistant Plasmodium falciparum in Malarial Infection: A Brief Review of Methods. J Trop Pediatr 0: fmp074v1-fmp074</ref><ref>Dondorp, A. M., Nosten, F., Yi, P., Das, D., Phyo, A. P., Tarning, J., Lwin, K. M., Ariey, F., Hanpithakpong, W., Lee, S. J., Ringwald, P., Silamut, K., Imwong, M., Chotivanich, K., Lim, P., Herdman, T., An, S. S., Yeung, S., Singhasivanon, P., Day, N. P.J., Lindegardh, N., Socheat, D., White, N. J. (2009). Artemisinin Resistance in Plasmodium falciparum Malaria. NEJM 361: 455-467 </ref><ref>Noedl, H., Socheat, D., Satimai, W. (2009). Artemisinin-Resistant Malaria in Asia. NEJM 361: 540-541 </ref><ref>Harald Noedl. Evidence of Artemisinin-Resistant Malaria in Western Cambodia. NEJM No 24 Volume 359:2619-2620 Dezember 2008 [http://content.nejm.org/cgi/content/full/359/24/2619]</ref>. Die Resistenzen entstanden dadurch daß | + | Im Grenzgebiet zwischen Thailand und Kambodscha beobachtet die Weltgesundheitsorganisation (WHO) zunehmend Resistenzen gegen das Malariamittel Artemisinin, das von der WHO kampagnenmäßig gegen die Malaria beworben wurde.<ref>Duffy PE, Sibley CH. Are we losing artemisinin combination therapy already? Lancet 2005;366:1908-1909</ref><ref>Jambou R, Legrand E, Niang M, et al. Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6. Lancet 2005;366:1960-1963</ref><ref>Noedl H. Artemisinin resistance: how can we find it? Trends Parasitol 2005;21:404-405</ref><ref>Quashie, N. B. (2009). Detection of Artemisinin-resistant Plasmodium falciparum in Malarial Infection: A Brief Review of Methods. J Trop Pediatr 0: fmp074v1-fmp074</ref><ref>Dondorp, A. M., Nosten, F., Yi, P., Das, D., Phyo, A. P., Tarning, J., Lwin, K. M., Ariey, F., Hanpithakpong, W., Lee, S. J., Ringwald, P., Silamut, K., Imwong, M., Chotivanich, K., Lim, P., Herdman, T., An, S. S., Yeung, S., Singhasivanon, P., Day, N. P.J., Lindegardh, N., Socheat, D., White, N. J. (2009). Artemisinin Resistance in Plasmodium falciparum Malaria. NEJM 361: 455-467</ref><ref>Noedl, H., Socheat, D., Satimai, W. (2009). Artemisinin-Resistant Malaria in Asia. NEJM 361: 540-541</ref><ref>Harald Noedl. Evidence of Artemisinin-Resistant Malaria in Western Cambodia. NEJM No 24 Volume 359:2619-2620 Dezember 2008 [http://content.nejm.org/cgi/content/full/359/24/2619]</ref> Die Resistenzen entstanden dadurch, dass: |